Advantages of 24-hour pH-impedance measurement in diagnosis and optimization of treatment approaches to gastroesophageal reflux disease in obese patients: Clinical observations
Abstract. The association between gastroesophageal reflux disease (GERD) and obesity has been proved in epidemiological studies. Accurate diagnosis of various GERD phenotypes (erosive and non-erosive, hypersensitive esophagus) and functional heartburn helps improve the effectiveness of therapy for patients with refractory heartburn. It is a known fact that 24-hour pH-impedance monitoring is an important part of the diagnostic algorithm for GERD. It allows the recording of all types of reflux into the esophagus, regardless of pH, and to make an assessment of their correlation with symptoms. Current article presents clinical observations of obese patients with GERD. A detailed examination demonstrated a link between symptoms and both acidic and non-acidic refluxes, enabling treatment adjustments and long-term remission.E.M. Mironova, G.L. Yurenev, D.S. Bordin
Keywords
gastroesophageal reflux disease
pH-impedance monitoring
obesity
non-acidic refluxes
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About the Authors
Ekaterina M. Mironova, MD, gastroenterologist, Federal Scientific and Clinical Center of FMBA; postgraduate student of the Department of propaedeutics of internal medicine and gastroenterology, Russian University of Medicine, Moscow, Russian Federation.E-mail: emmironova89@gmail.com
ORCID: https://orcid.org/0000-0003-2264-1047
Georgy L. Yurenev, MD, Dr. Sci. (Medicine), professor, Department of propaedeutics of internal medicine and gastroenterology, Russian University of Medicine, Moscow, Russian Federation.
E-mail: yurenev@list.ru
ORCID: https://orcid.org/0000-0001-8181-8813. eLibrary SPIN: 6449-9694
Dmitry S. Bordin, MD, Dr. Sci. (Medicine), head of the Department of pancreatic, biliary, and upper digestive tract pathology, A.S. Loginov Moscow Clinical Research Center; professor of the Department of propaedeutics of internal medicine and gastroenterology, Russian University of Medicine; professor of the Department of general medical practice and family medicine of the Faculty of postgraduate education, Tver State Medical University, Tver, Russian Federation.
E-mail: d.bordin@mknc.ru
ORCID: https://orcid.org/0000-0003-2815-3992. eLibrary SPIN: 6331-6323
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