Peripartum cardiomyopathy with high arrhythmogenic activity: A clinical case
Abstract. Current article is dedicated to a pressing issue: decreased left ventricular (LV) ejection fraction in the third trimester of pregnancy, its risk factors, and causes. According to the literature and authors’ own data, the incidence of such cases has increased significantly in recent years. Much attention is being paid to the most common cause of this condition: peripartum cardiomyopathy (PPCM). PPCM, or postpartum cardiomyopathy, is an idiopathic cardiomyopathy characterized by heart failure (HF) secondary to LV systolic dysfunction at the end of pregnancy or within a few months postpartum, in the absence of other identifiable causes of HF. The prevalence, etiology, and pathogenesis of this disease are still remaining to be unknown for sure. The article presents a clinical case of a patient with PPCM, on the basis of which the discussion concerning its causes, possible risk factors, and treatment principles is carried out. In addition to a reduced LV ejection fraction, the patient had high arrhythmogenic cardiomyocytes activity, necessitating not only full standard drug therapy for HF but also close attention to cardiac rhythm control.S.D. Mayanskaya, A.A. Gilmanov, E.I. Safina, K.N. Ermakova, S. A. Fayzrakhmanova, A.S. Mironova, M.M. Mangusheva
Keywords
peripartum cardiomyopathy
risk factors for peripartum cardiomyopathy
heart failure
preterm labor
ventricular arrhythmia
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About the Authors
Svetlana D. Mayanskaya, MD, Dr. Sci.(Medicine), professor of the Department of hospital therapy, Kazan State Medical University, Kazan, Russian Federation.E-mail: Smayanskaya@mail.ru
ORCID: https://orcid.org/0000-0001-6701-5395. Scopus ID: 6507459643. eLibrary SPIN: 1069-1400
Albert A. Gilmanov, MD, head of the Department of cardiology, Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, Kazan, Russian Federation.
E-mail: bip1@rambler.ru
ORCID: https://orcid.org/0000-0002-6510-2732. eLibrary SPIN: 4835-4715
Elvira I. Safina, MD, cardiologist at Department of cardiology, Republican Clinical Hospital of the Ministry of Healthcare of the Republic of Tatarstan, Kazan, Russian Federation.
E-mail: kamilya.erm@mail.ru
ORCID: https://orcid.org/0000-0001-8789-178X
Kamilia N. Ermakova, MD, clinical resident of the Department of hospital therapy, Kazan State Medical University, Kazan, Russian Federation.
E-mail: kamilya.erm@mail.ru
ORCID: https://orcid.org/0009-0004-7109-4275. Scopus ID: 59916154100
Susanna A. Fayzrakhmanova, MD, clinical resident of the Department of hospital therapy, Kazan State Medical University, Kazan, Russian Federation.
E-mail: fayzrakhmanova.susanna13@mail.ru
ORCID: https://orcid.org/0009-0001-7243-9843
Arina S. Mironova, MD, clinical resident of the Department of hospital therapy, Kazan State Medical University, Kazan, Russian Federation.
E-mail: Arinamironova7572@gmail.com
ORCID: https://orcid.org/0009-0004-8038-0054
Marzia M. Mangusheva, MD, PhD (Medicine), associate professor of the Department of hospital therapy, Kazan State Medical University, Kazan, Russian Federation.
E-mail: mangushevam@mail.ru
ORCID: https://orcid.org/0000-0002-6425-4216. eLibrary SPIN: 4668-4053
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