Choice of anticoagulant therapy in an elderly patient with atrial fibrillation and high risk of hemorrhage
Abstract. Atrial fibrillation more often occurs in elderly patients (≥ 65 years) with polypharmacy and high risk of hemorrhages, complicating anticoagulant therapy. Direct oral anticoagulants demonstrate advantages over warfarin in terms of efficacy and safety. Data from a number of studies (RE-LY, ROCKET AF, ARISTOTLE, SAFIR AC), indicating that rivaroxaban, due to the optimal balance of efficacy, safety and ease of use, can be considered as a drug of choice in elderly patients with atrial fibrillation, especially with a high risk of hemorrhages, chronic kidney disease and concomitant atherosclerosis are analyzed in the article.Stavtseva Yu.V, Goreva L.A.
Keywords
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About the Authors
Yulia V. Stavtseva, MD, PhD (Medicine), associate professor of the Department of internal medicine with a course in cardiology and functional diagnostics named after academician V.S. Moiseyev, Medical Institute of RUDN University. Address: 117198, Moscow, 6 Miklukho-Maklaya St.E-mail: Y.stavtseva@gmail.com
ORCID: https://orcid.org/0000-0001-9323-4444. Scopus ID: 57164774900. eLibrary SPIN: 4696-6705
Lybov A. Goreva, MD, PhD (Medicine), associate professor of the Department of internal medicine with a course in cardiology and functional diagnostics named after academician V.S. Moiseyev, Medical Institute of RUDN University. Address: 117198, Moscow, 6 Miklukho-Maklaya St.
E-mail: v.melkumyan@mail.ru
ORCID: https://orcid.org/0000-0002-5456-8545. Scopus ID: 57204782974. eLibrary SPIN: 7613-4089