Rapid course of severe diabetic retinopathy
Abstract. Progress in the treatment of vascular complications of diabetes mellitus (DM) has not solved the problem of timely diagnosis of diabetic retinopathy (DR), which is detected in most cases at an advanced stage of DM. DR is a common microvascular complication of DM and the leading cause of preventable blindness in people of working age. The presented clinical case demonstrates a patient with complete loss of vision in the first 6 years from the onset of type 2 DM. Despite multiple attempts of anti-VEGF therapy, proliferative retinopathy in this case was complicated by corneal dystrophy, rubeosis of iridis, terminal glaucoma, and development of blindness in both eyes. Due to the risk of rapid progression of DR, annual examination by ophthalmologist is critical to preserve patients’ vision and improve their quality of life. The article considers potential risk factors for severe DR, and discusses methods for early diagnosis and prevention of this complication.Nadybina M.N., Ushanova F.O., Demidova T.Yu.
Keywords
diabetes mellitus
diabetic retinopathy
anti-VEGF therapy
glaucoma
neovascularization
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About the Authors
Margarita N. Nadybina, MD, postgraduate student of the Department of endocrinology of the Institute of Clinical Medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University). Address: 117513, Moscow, 1/6 Ostrovityanova St.E-mail: mita0098@gmail.com
ORCID: https://orcid.org/0000-0002-6891-1711. Scopus ID: 57219236724
Fatima O. Ushanova, MD, PhD (Medicine), associate professor of the Department of endocrinology of the Institute of Clinical Medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University). Address: 117513, Moscow, 1/6 Ostrovityanova St.
E-mail: fati_2526@mail.ru
ORCID: https://orcid.org/0000-0001-5512-6899. Scopus ID: 57224575299. eLibrary SPIN: 3361-8564
Tatyana Yu. Demidova, MD, Dr. Sci. (Medicine), professor, head of the Department of endocrinology of the Institute of Clinical Medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University). Address: 117513, Moscow, 1/6 Ostrovityanova St.
E-mail: t.y.demidova@gmail.com
ORCID: https://orcid.org/0000-0001-6385-540X. Scopus ID: 7003771623. eLibrary SPIN: 9600-9796
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