Generalized destructive tuberculosis process with drug resistance of a causative agent in a vegetarian family
Abstract. Tuberculosis patients who suffer from malnutrition have more severe forms of the disease, high risks of death and poor treatment outcomes. In this regard, we present a clinical observation of a 38-year-old female patient and a 42-year-old male patient (husband and wife) hospitalized at the Central research institute of tuberculosis in February 2024 in a severe clinical condition. Upon admission, the patients had severe inflammatory syndrome and generalized tuberculous process in lung tissue with massive bacterial excretion. Moreover, there was a pronounced protein-energy deficiency, which led to the rapid progression of a specific process. A comprehensive approach is needed to treat that certain category of patients, which should not be limited to the use of anti-tuberculosis chemotherapy drugs.Chumovatov N.V., Chernykh N.A., Komissarova O.G.
Keywords
tuberculosis
drug resistance
comprehensive approach to tuberculosis treatment
malnutrition
vegetarianism
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About the Authors
Nikita V. Chumovatov, MD, PhD (Medicine), researcher at the Department of phthisiology, Central Research Institute of Tuberculosis. Address: 107564, Moscow, 2 Yauzskaya Alley.E-mail: Necro5412@mail.ru
ORCID: https://orcid.org/0000-0001-8745-7940. Scopus ID: 57459472600. eLibrary SPIN: 7088-5717
Natalya A. Chernykh, MD, PhD (Medicine), senior researcher at the Department of phthisiology, Central Research Institute of Tuberculosis. Address: 107564, Moscow, 2 Yauzskaya Alley.
E-mail: natadok@inbox.ru
ORCID: https://orcid.org/0000-0001-6787-2362. Scopus ID: 36957272200. eLibrary SPIN: 9144-7729
Oksana G. Komissarova, MD, Dr. Sci. (Medicine), associate professor, deputy director for scientific and medical work of the Department of phthisiology, Central Research Institute of Tuberculosis, professor of the Department of phthisiology, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University). Address: 107564, Moscow, 2 Yauzskaya Alley.
E-mail: oksana.komissarova.72@mail.ru
ORCID: https://orcid.org/0000-0003-4427-3804. Scopus ID: 15051823500. eLibrary SPIN: 2969-5800
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