Diagnostic capabilities of the analysis of exhaled air biochemical composition in respiratory diseases
Abstract. Respiratory diseases diagnostics is a complex task for modern medicine, especially when using traditional methods associated with invasiveness and risks for patients. Exhaled air analysis based on the study of volatile organic compounds offers a non-invasive, rapid and accurate approach for detecting diseases such as chronic obstructive pulmonary disease, asthma, lung cancer, pneumonia and COVID-19. The aim of the research is to evaluate the diagnostic capabilities of exhaled air biochemical analysis for detection of various respiratory pathologies and determine the key advantages and limitations of this method. Exhaled air analysis is a promising diagnostic tool due to its non-invasiveness, high sensitivity and the possibility of repeated use. Despite the need for standardization of the method, its use has significant potential for improving the diagnosis and monitoring of respiratory diseases in clinical practice.Teteneva A.V., Bespalova I.D., Yarovoy N.D., Chernov V.I., Sachkov V.I., Sorokina T.V., Nesterovich S.V., Radionov D.I., Radionova E.V.
Keywords
References
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About the Authors
Anna V. Teteneva, MD, Dr. Sci. (Medicine), professor of the Department of propaedeutics of internal diseases with a course in therapy of the Faculty of pediatrics, Siberian State Medical University of the Ministry of Healthcare of Russia, deputy chief physician for clinical and expertise work of Primary Healthcare Unit No. 2 of the Department of Healthcare of Tomsk region. Address: 634050, Tomsk, 2 Moskovsky Tract.E-mail: anna.dubodelova@mail.ru
ORCID: https://orcid.org/0000-0002-4323-2798. Scopus ID: 57214109808. eLibrary SPIN: 9472-4472
Inna D. Bespalova, MD, Dr. Sci. (Medicine), head and professor of the Department of propaedeutics of internal diseases with a course in therapy of the Faculty of pediatrics, Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky Tract.
E-mail: bespalova.id@ssmu.ru
ORCID: https://orcid.org/0000-0002-4513-6329. Scopus ID: 55820749900. eLibrary SPIN: 6852-6200
Nikolay D. Yarovoy, resident of the Department of biochemistry and molecular biology with the course of clinical laboratory diagnostics, Siberian State Medical University of the Ministry of Healthcare of Russia, physician-statistician of Primary Healthcare Unit No. 2 of the Department of Healthcare of Tomsk region. Address: 634050, Tomsk, 2 Moskovsky Tract.
E-mail: koly-yarovoy@yandex.ru
ORCID: https://orcid.org/0000-0003-3619-6095. eLibrary SPIN: 1707-4330
Vladimir I. Chernov, MD, Dr. Sci. (Medicine), professor, corresponding member of RAS, deputy director for research and innovation work, Tomsk National Research Medical Center of the Russian Academy of Sciences, head of the Department of radionuclide therapy and diagnostics of the Research institute of oncology, Tomsk National Research Medical Center of the Russian Academy of Sciences. Address: 634009, Tomsk, 5 Kooperativny Lane.
E-mail: achernov@tnimc.ru
ORCID: https://orcid.org/0000-0001-8753-7916
Viktor I. Sachkov, Dr. Sci. (Chemistry), associate professor, head of the Department of chemical technologies, head of the Innovation and Technology Center of Siberian Physics and Technology Institute, National Research Tomsk State University. Address: 634050, Tomsk, 36 Lenina Avenue.
E-mail: Vicsachkov@outlook.com
ORCID: https://orcid.org/0000-0001-7866-274X
Tatiana V. Sorokina, MD, head of the Therapeutic Clinic – therapist at Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky Tract.
E-mail: gbsmp.sorokinatatyana@mail.ru
ORCID: https://orcid.org/0000-0002-6264-4632
Sofia V. Nesterovich, MD, PhD (Medicine), chief physician of Siberian State Medical University of the Ministry of Healthcare of Russia. Address: 634050, Tomsk, 2 Moskovsky Tract.
E-mail: nesterovich.sv@ssmu.ru
ORCID: https://orcid.org/0000-0003-2098-2964
Denis I. Radionov, MD, therapist at Minusinsk Interdistrict Hospital. Address: 662606, Minusinsk, 2a Botanicheskaya St.
E-mail: radionovdenis12@gmail.ru
ORCID: https://orcid.org/0009-0004-2863-2736
Ekaterina V. Radionova, MD, therapist at Minusinsk Interdistrict Hospital. Address: 662606, Minusinsk, 2a Botanicheskaya St.
E-mail: Opoldnik@yandex.ru
ORCID: https://orcid.org/0000-0002-0696-2951