Metabolic-associated fatty liver disease: Difficulties in diagnostics and ways to overcome them
Abstract. The article presents a review of modern approaches to the diagnosis of metabolic-associated fatty liver disease with an emphasis on the difficulties of diagnosis verification in patients with normal body mass index. New diagnostic criteria proposed in 2024 clinical guidelines, as well as the possibilities of using transient elastography with a controlled attenuation parameter as a promising method of non-invasive diagnostics are considered. Particular attention is paid to the phenotype of non-obese metabolic-associated fatty liver disease, its prevalence and pathophysiological peculiarities. The practical significance of the review lies in generalization of modern data that contribute to the timely detection of the disease in outpatient practice.Minosyan I.S., Tarasova O.I., Kokorin V.A.
Keywords
References
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About the Authors
Ilona S. Minosyan, MD, postgraduate student of the Department of hospital therapy with courses in endocrinology, hematology and clinical laboratory diagnostics of the Medical institute, RUDN University, gastroenterologist-hepatologist at Professor P.P. Ogurtsov Liver Research Center of Clinical and Diagnostic Center, RUDN University. Address: 117198, Moscow, 8 Mikloukho-Maklaya St.E-mail: minosyan_is@pfur.ru
ORCID: https://orcid.org/0009-0006-1327-1557. eLibrary SPIN: 4244-4658
Olga I. Tarasova, MD, PhD (Medicine), associate professor, associate professor of the Department of hospital therapy with courses in endocrinology, hematology and clinical laboratory diagnostics of the Medical institute, RUDN University. Address: 117198, Moscow, 8 Mikloukho-Maklaya St.
E-mail: tarasova_oi@pfur.ru
ORCID: https://orcid.org/0000-0001-6376-8189. Scopus ID: 56362675300. eLibrary SPIN: 7367-7415
Valentin A. Kokorin, MD, Dr. Sci.(Medicine), associate professor, head of the Department of hospital therapy with courses in endocrinology, hematology and clinical laboratory diagnostics of the Medical institute, RUDN University, professor of the Department of hospital therapy named after academician P.E. Lukomsky of the Institute of clinical medicine, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University). Address: 117198, Moscow, 8 Miklukho-Maklaya St.
E-mail: kokorin_va@pfur.ru
ORCID: https://orcid.org/0000-0001-8614-6542. Scopus ID: 56053021100. eLibrary SPIN: 9772-2288