ISSN 2412-4036 (print)
ISSN 2713-1823 (online)

Enhanced recovery after cardiac surgery: ERACS concept, the role of the therapist, and local intervention

O.G. Musaev, V.I. Vechorko, A.O. Shevchenko, K.B. Lebedeva, N.V. Viktorov

1) O.M. Filatov Moscow City Clinical Hospital No. 15, Moscow, Russian Federation; 2) N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
Abstract. Enhanced recovery after cardiac surgery (ERACS) program integrates preoperative correction of modifiable risk factors, standardized anesthetic and surgical management, multimodal analgesia, early reinstatement of nutrition and activity, complication prevention, and continuity of care.
The aim of the review was to summarize current data on ERACS, define the role of the physician, and present principles for its local implementation. A targeted, non-systematic search of relevant scientific sources was performed in PubMed, Cochrane Library, and Google Scholar for the period 2019–2026. The most consistent results presented in the reviewed literature are associated with a reduction in the duration of mechanical ventilation, intensive care unit stay, and hospitalization with the implementation of ERACS. However, the impact of ERACS on mortality and severe complications remains poorly understood. The article also discusses monitoring of protocol component implementation and maintaining a local registry.

Keywords

enhanced recovery after surgery
ERACS
cardiac surgery
perioperative management
preoperative optimization
multimodal analgesia
early mobilization
therapist

References

  1. Engelman DT, Ben Ali W, Williams JB, Perrault LP, Reddy VS, Arora RC, et al. Guidelines for perioperative care in cardiac surgery: Enhanced recovery after surgery society recommendations. JAMA Surg. 2019;154(8):755–66.

    PMID: 31054241. https://doi.org/10.1001/jamasurg.2019.1153

  2. Grant MC, Crisafi C, Alvarez A, Arora RC, Brindle ME, Chatterjee S, et al. Perioperative care in cardiac surgery: A Joint Consensus Statement by the Enhanced Recovery After Surgery Cardiac Society, ERAS International Society, and The Society of Thoracic Surgeons. Ann Thorac Surg. 2024;117(4):669–89.

    PMID: 38284956. https://doi.org/10.1016/j.athoracsur.2023.12.006

  3. Mertes PM, Kindo M, Amour J, Baufreton C, Camilleri L, Caus T, et al. Guidelines on enhanced recovery after cardiac surgery under cardiopulmonary bypass or off-pump. Anaesth Crit Care Pain Med. 2022;41(3):101059.

    PMID: 35504126. https://doi.org/10.1016/j.accpm.2022.101059

  4. Hirji SA, Salenger R, Boyle EM, Williams J, Reddy VS, Grant MC, et al. Expert Consensus of data elements for collection for enhanced recovery after cardiac surgery. World J Surg. 2021;45(4):917–25.

    PMID: 33521878. https://doi.org/10.1007/s00268-021-05964-1

  5. Guinn NR, Schwartz J, Arora RC, Morton-Bailey V, Aronson S, Brudney CS, Bennett-Guerrero E; Perioperative Quality Initiative (POQI-8) and the Enhanced Recovery After Surgery-Cardiac Society (ERAS-C) Investigators. Perioperative Quality Initiative and Enhanced Recovery After Surgery-Cardiac Society Consensus Statement on the management of preoperative anemia and iron deficiency in adult cardiac surgery patients. Anesth Analg. 2022;135(3):532–44.

    PMID: 35977363. https://doi.org/10.1213/ANE.0000000000006148

  6. Howard-Quijano K, Shore-Lesserson L, Osho A, Raphael J, Rove JY, Panigrahi AK, et al; American Heart Association Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology. Perioperative anemia and patient blood management in cardiac surgery: A Scientific Statement from the American Heart Association. Circulation. 2026;154(6):e243–57.

    PMID: 42324995. https://doi.org/10.1161/CIR.0000000000001446

  7. Grant MC, Chappell D, Gan TJ, Manning MW, Miller TE, Brodt JL; PeriOperative Quality Initiative (POQI) and the Enhanced Recovery After Surgery (ERAS) Cardiac Society Workgroup. Pain management and opioid stewardship in adult cardiac surgery: Joint consensus report of the PeriOperative Quality Initiative and the Enhanced Recovery After Surgery Cardiac Society. J Thorac Cardiovasc Surg. 2023;166(6):1695–706.e2.

    PMID: 36868931. https://doi.org/10.1016/j.jtcvs.2023.01.020

  8. Паромов К.В., Свирский Д.А., Киров М.Ю. Эволюция и перспективы анестезии и методов обезболивания при коронарном шунтировании. Вестник Российской академии медицинских наук. 2023;78(6):541–548. [Paromov KV, Svirskii DA, Kirov MYu. Evolution and perspectives of anesthesia and analgesia techniques for coronary artery bypass grafting. Vestnik Rossiiskoy akademii meditsinskikh nauk = Annals of the Russian Academy of Medical Sciences. 2023;78(6):541–548 (In Russ.)].

    EDN: NRKZOL. https://doi.org/10.15690/vramn8811

  9. Паромов К.В., Свирский Д.А., Киров М.Ю. Регионарные методики в практике кардиоанестезиолога: есть ли выбор? Анестезиология и реаниматология (Медиа Сфера). 2021;(6):75–81. [Paromov KV, Svirskii DA, Kirov MYu. Regional anesthesia in cardiac surgery: is there a choice? Anesteziologiya i reanimatologiya (Media Sfera) = Russian Journal of Anaesthesiology and Reanimatology. 2021;(6):75–81 (In Russ.)].

    EDN: QNXFCS. https://doi.org/10.17116/anaesthesiology202106175

  10. Salenger R, Arora RC, Bracey A, D’Oria M, Engelman DT, Evans C, et al. Cardiac surgical bleeding, transfusion, and quality metrics: joint consensus statement by the Enhanced Recovery After Surgery Cardiac Society and Society for the Advancement of Patient Blood Management. Ann Thorac Surg. 2025;119(2):280–95.

    PMID: 39222899. https://doi.org/10.1016/j.athoracsur.2024.06.039

  11. Silvetti S, Paternoster G, Abelardo D, Ajello V, Aloisio T, Baiocchi M, et al. Recommendations for fast-track extubation in adult cardiac surgery patients: A consensus statement. Minerva Anestesiol. 2024;90(11):957–68.

    PMID: 39545652. https://doi.org/10.23736/S0375-9393.24.18267-3

  12. Kanejima Y, Shimogai T, Kitamura M, Ishihara K, Izawa KP. Effect of early mobilization on physical function in patients after cardiac surgery: A systematic review and meta-analysis. Int J Environ Res Public Health. 2020;17(19):7091.

    PMID: 32998202. https://doi.org/10.3390/ijerph17197091

  13. Aldecoa C, Bettelli G, Bilotta F, Sanders RD, Aceto P, Audisio R, et al. Update of the European Society of Anaesthesiology and Intensive Care Medicine evidence-based and consensus-based guideline on postoperative delirium in adult patients. Eur J Anaesthesiol. 2024;41(2):81–108.

    PMID: 37599617. https://doi.org/10.1097/EJA.0000000000001876

  14. Zhang Y, Chong JH, Harky A. Enhanced recovery after cardiac surgery and its impact on outcomes: A systematic review. Perfusion. 2022;37(2):162–74.

    PMID: 33468017. https://doi.org/10.1177/0267659121988957

  15. Spadaccio C, Salsano A, Pisani A, Nenna A, Nappi F, Osho A, et al. Enhanced recovery protocols after surgery: A systematic review and meta-analysis of randomized trials in cardiac surgery. World J Surg. 2024;48(4):779–90.

    PMID: 38423955. https://doi.org/10.1002/wjs.12122

  16. Diz-Ferreira E, Díaz-Vidal P, Fernández-Vázquez U, Gil-Casado C, Luna-Rojas P, Diz JC. Effect of Enhanced Recovery After Surgery (ERAS) programs on perioperative outcomes in patients undergoing cardiac surgery: A systematic review and meta-analysis. J Cardiothorac Vasc Anesth. 2025;39(5):1325–34.

    PMID: 39952836. https://doi.org/10.1053/j.jvca.2025.01.036

  17. Hoogma DF, Meeusen I, Coppens S, Verbrugghe P, van den Eynde J, Engelman DT, et al. Efficacy of enhanced recovery programmes for cardiac surgery: A systematic review and meta-analysis. Br J Anaesth. 2025;135(1):31–39.

    PMID: 40287362. PMCID: PMC12597454. https://doi.org/10.1016/j.bja.2025.03.019

  18. Ltaief Z, Verdugo-Marchese M, Carel D, Gunga Z, Nowacka A, Melly V, et al. Implementation of cardiac enhanced recovery after surgery at Lausanne University Hospital, our roadbook to certification. Interdiscip Cardiovasc Thorac Surg. 2024;39(1):ivae118.

    PMID: 38885412. PMCID: PMC11219240. https://doi.org/10.1093/icvts/ivae118

  19. Williams JB, McConnell G, Allender JE, Woltz P, Kane K, Smith PK,et al. One-year results from the first US-based Enhanced Recovery After Cardiac Surgery (ERAS Cardiac) program. J Thorac Cardiovasc Surg. 2019;157(5):1881–88.

    PMID: 30665758. https://doi.org/10.1016/j.jtcvs.2018.10.164

  20. Grant MC, Isada T, Ruzankin P, Whitman G, Lawton JS, Dodd-O J, Barodka V; Johns Hopkins Enhanced Recovery Program for the Cardiac Surgery Working Group. Results from an enhanced recovery program for cardiac surgery. J Thorac Cardiovasc Surg. 2020;159(4):1393–402.e7.

    PMID: 31279510. https://doi.org/10.1016/j.jtcvs.2019.05.035

  21. Yazdchi F, Hirji S, Harloff M, McGurk S, Morth K, Zammert M, et al. Enhanced recovery after cardiac surgery: A propensity-matched analysis. Semin Thorac Cardiovasc Surg. 2022;34(2):585–94.

    PMID: 34089824. https://doi.org/10.1053/j.semtcvs.2021.05.010

  22. Salenger R, Holmes SD, Rea A, Yeh J, Knott K, Born R, et al. Cardiac enhanced recovery after surgery: Early outcomes in a community setting. Ann Thorac Surg. 2022;113(6):2008–17.

    PMID: 34352198. https://doi.org/10.1016/j.athoracsur.2021.06.072

  23. Malvindi PG, Bifulco O, Berretta P, Galeazzi M, Alfonsi J, Cefarelli M, et al. The enhanced recovery after surgery approach in heart valve surgery: A systematic review of clinical studies. J Clin Med. 2024;13(10):2903.

    PMID: 38792445. PMCID: PMC1112194. https://doi.org/10.3390/jcm13102903

  24. Gregory AJ, Teeter E, Galhardo C Jr, Ibekwe SO, Grocott HP, Popescu WM, Grant MC; SCA ERACS Survey Writing Group. Enhanced recovery after cardiac surgery: Society of Cardiovascular Anesthesiologists (SCA) and American Society of Anesthesiologists (ASA) Membership Survey. J Cardiothorac Vasc Anesth. 2026;40(6):1722–39.

    PMID: 41846213. https://doi.org/10.1053/j.jvca.2026.02.017

About the Authors

Orkhan G. Musaev, MD, head of the Department of cardiac surgery, cardiovascular surgeon, O.M. Filatov Moscow City Clinical Hospital No. 15, Moscow, Russian Federation.
E-mail: bhhb@mail.ru
ORCID: https://orcid.org/0000-0001-9728-1563
Valery I. Vechorko, MD, Dr. Sci. (Medicine), chief physician at O.M. Filatov Moscow City Clinical Hospital No. 15; head and professor of the Department of ambulance and emergency medical care, N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation.
E-mail: vvechorko@yandex.ru
ORCID: https://orcid.org/0000-0003-3568-5065
Alexey O. Shevchenko, MD, Dr. Sci. (Medicine), professor, corresponding member of RAS, acting head of the regional vascular center, O.M. Filatov Moscow City Clinical Hospital No. 15; professor, head of the Department of cardiology of the Institute of continuing professional development, N.I. Pirogov Russian National Research Medical University; chairman of the Expert Council of Academician V.I. Shumakov National Medical Research Center for Transplantology and Artificial Organs, Moscow, Russian Federation.
E-mail: alxxshevchenko@aol.com
ORCID: https://orcid.org/0000-0003-4719-9486
Karina B. Lebedeva, MD, cardiovascular surgeon at O.M. Filatov Moscow City Clinical Hospital No. 15; assistant at the Department of hospital surgery No. 1 named after V.S. Mayat of the Institute of surgery, N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation.
E-mail: kardamowa.carina@yandex.ru
ORCID: https://orcid.org/0009-0009-6456-9021
Nikolay V. Viktorov, resident of the Department of hospital surgery No. 1 named after V.S. Mayat of the Institute of surgery, N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation.
E-mail: nv.viktorov@outlook.com
ORCID: https://orcid.org/0009-0002-3494-8644