Listeriosis in immunocompromised patients: A clinical observation
Abstract. Listeriosis is an infectious disease caused by bacteria of Listeria genus, which are widespread in environment due to the large number of natural reservoirs. In the structure of infectious diseases, this nosological form is quite rare due to the low susceptibility of healthy individuals to it. However, listeriosis has a serious danger to patients receiving immunosuppressive therapy, having immunodeficiency conditions of various etiologies, as well as to pregnant women. This article presents clinical observations of patients developing listeria infection in the form of listeria meningoencephalitis and septicemia. These observations illustrate clinical course of the disease, complexities of its diagnosis, and importance of promptly administering etiotropic therapy. Laboratory and instrumental data are presented, and pathogenetic mechanisms of infection development in immunocompromised patients are discussed.Filin V.I., Ponezheva Zh.B., Mannanova I.V., Miryanova T.V.
Keywords
listeriodis
Listeria monocytogenes
meningoencephalitis
septicemia
immunosuppression
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About the Authors
Vladimir I. Filin, MD, resident physician of Central Research Institute of Epidemiology of Rospotrebnadzor, specializing in infectious diseases. Address: 111123, Moscow, 3a Novogireevskaya St.E-mail: mr.filin1@yandex.ru
Zhanna B. Ponezheva, MD, Dr. Sci. (Medicine), head of the Clinical Department of infectious pathology, Central Research Institute of Epidemiology of Rospotrebnadzor. Address: 111123, Moscow, 3a Novogireevskaya St.
E-mail: doktorim@mail.ru
ORCID: https://orcid.org/0000-0002-6539-4878
Irina V. Mannanova, MD, PhD (Medicine), senior researcher at the Clinical Department of infectious pathology, Central Research Institute of Epidemiology of Rospotrebnadzor. Address: 111123, Moscow, 3a Novogireevskaya St.
E-mail: irinasemenova07@rambler.ru
ORCID: https://orcid.org/0000-0003-2244-8810
Tatyana V. Miryanova, MD, head of the Department, infectious disease physician of Infectious Diseases Clinical Hospital No. 1 of the Department of Healthcare of Moscow. Address: 125310, Moscow, 63/c2 Volokolamskoe Highway.
E-mail: MiryanovaTV@Zdrav.mos.ru
