Options of therapeutic effects of a complex drug in patients with external bacterial otitis
Abstract. Bacterial external otitis is a disease with which patients often apply to otolaryngologist, therapist, and general practitioner. In recent years, in the presence of growing polyresistant strains of microorganisms, a reasonable limitation of the systemic use of antibiotics and their possible replacement by local treatment remedies is appreciated. Current article discusses the possibility of combined use of topical drugs having antibacterial, anti-inflammatory and analgesic effects in order to quickly relieve the main symptoms of that disease. Basing on the analysis of literary data, it was concluded that ear drops containing neomycin, polymyxin B and lidocaine are effective in the treatment of acute and chronic forms of external bacterial otitis, including those caused by Pseudomonas aeruginosa, are able to quickly relieve pain and other signs of inflammation, significantly improving general well-being of the patient without the need for additional use of anti-inflammatory and analgesic drugs.Gurov A.V., Yushkina M.A., Muzhichkova A.V.
Keywords
external bacterial otitis
neomycin
polymyxin B
lidocaine
local therapy
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About the Authors
Alexander V. Gurov, MD, Dr. Sci. (Medicine), professor of the Department of otolaryngology named after academician B.S. Preobrazhensky of the Institute of Surgery and of the Department of microbiology and virology of the Institute of preventive, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University), senior researcher at L.I. Sverzhevsky Research Clinical Institute of Otolaryngology of the Department of Healthcare of Moscow. Address: 117513, Moscow, 1/6 Ostrovityanova St.E-mail: alex9999@inbox.ru
ORCID: https://orcid.org/0000-0001-9811-8397. Scopus ID: 7005510515. eLibrary SPIN: 9354-4813
Marina A. Yushkina, MD, PhD (Medicine), associate professor of the Department of otolaryngology named after academician B.S. Preobrazhensky of the Institute of Surgery, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University), associate professor of the Educational Department, L.I. Sverzhevsky Research Clinical Institute of Otolaryngology of the Department of Healthcare of Moscow. Address: 117513, Moscow, 1/6 Ostrovityanova St.
E-mail: yushkina.ma@gmail.com
ORCID: https://orcid.org/0000-0002-9823-1047. Scopus ID: 55344662200. eLibrary SPIN: 5281-4189
Anna V. Muzhichkova, MD, PhD (Medicine), assistant at the Department of otolaryngology named after academician B.S. Preobrazhensky of the Institute of Surgery, N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia (Pirogov University), associate professor of the Educational Department, L.I. Sverzhevsky Research Clinical Institute of Otolaryngology of the Department of Healthcare of Moscow. Address: 117513, Moscow, 1/6 Ostrovityanova St.
E-mail: touch83@mail.ru
ORCID: https://orcid.org/0000-0001-5940-9343. Scopus ID: 44061848300. eLibrary SPIN: 5180-3626
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